32 SERIES (VIDEO 5)

hi everyone today we are going to
discuss 32 important points from the
topic oral aspects of metabolic diseases
now these are important from need point
of view now we shall see the very first
point delayed eruption is seen in the
following conditions such as rickets or
vitamin D deficiency Down syndrome
hypothyroidism Lido cranial dysplasia
cherub ism and achondroplasia
point number two Marrissa form xanthoma
is a condition where presence of large
for me cells in the connective tissue is
seen between the papillae point number
three human copper deficiency diseases
of importance are hepatolan' ticular
degeneration that is more often li
called as wilson's disease and mink
syndrome that is still e or kinky hair
syndrome now the left corner image shows
us the characteristic skin rash you -
Gnaeus in deficiency especially in areas
exposed to sunlight now this condition
is called as castles necklace so that's
going to be a fourth point now moving on
to fifth point Addison's disease is due
to insufficiency of adrenal cortex that
shows deep chocolate pigmentation of
oral mucosa point number six Cushing
syndrome is produced by ACTH secreting
tumors that also produced diffused
mucocutaneous pigmentation similar to
adrenal insufficiency point number seven
the systemic disease that may increase
oral male noses piece albright syndrome
point number eight hypophosphite Asia is
the condition where deficiency of enzyme
alkaline phosphatase along with
excretion of phosphorus an ala mine in
urine and absence of cementum is seen
whereas hypophosphatemia is vitamin D
resistant rickets
point number nine osteomalacia is a
condition where
is seen in newly-formed organic bone
matrix point number 10
rickets is a condition where defect is
seen in the mineralization of
endochondral new pole point number 11
deficiency of vitamins a CD causes
enamel hypoplasia point number 12
alcoholic patients with chronic thiamine
deficiency shows CNS manifestations such
as vernix encephalopathy now along with
this if there is loss of memory as well
it is known as vernix korok or syndrome
now that's going to be a point number 13
now moving on to point number 14 in
porphyria the sidious and permanent
teeth may show a red or brownish
discoloration and exhibit red
fluorescence point number 15 her
Lascelles or ghazal cells that is
abnormal fibroblasts are the
characteristic histological finding of
furless syndrome
whereas in cytoplasm of circulating
lymphocytes we find metachromatic
granules or rly bodies point number 16
claw hands broadening of mandible with a
widened econo distance are features of
hurler syndrome point number 17 draw a
beefy tongue and ball tongue of Sandwich
is associated with nian deficiency point
number 18 magenta color tongue is
associated with riboflavin deficiency
point number 19 molars glossitis or
hunters glossitis is associated with
vitamin b12 deficiency point number 20
the old term histiocytosis X is replaced
by new term called Langerhans cell
histiocytosis that is LCH the presence
of Burdick's granules is the
characteristic finding in Langerhans
cell histiocytosis point number 21
generalized gingival inflammation
profuse elevation and scalding or skin
from palm and foot is associated with
Hey
metal poisoning or toxicity now LED
mercury bismuth and arsenic are the
metals that cause heavy metal poisoning
or toxicity these get deposited in the
Ural tissues and extravasated in areas
of chronic inflammation
now additional to this the systemic
signs and symptoms that may include our
behavioral changes neurologic disorders
intestinal pain and solarium join number
22 diabetes insipidus bone lesions and
exophthalmos is seen in hand Sheila
Christian disease point number 23 giant
cells are characteristic histopathologic
finding in the case of brown tumor of
hyperparathyroidism
point number 24 bone pain bone cyst
fractures and renal stones are
characteristics of hyperparathyroidism
point number 25 hypogonadism
developmental delay loss of taste and
smell is due to deficiency of zinc point
number 26 increase in height of mandible
with increase in interdental spaces in
elderly man is due to high particularism
point number 27 the normal serum calcium
level is 9 to 11 milligram percentage
now point number 28 lamina dura is lost
or partially lost in the case of
hyperparathyroidism point number 29
tetiny is associated with a low
concentration of ionized calcium in the
serum point number 30 intestinal
absorption of calcium is decreased by
phytic acid point number 31 amyloid can
be demonstrated by special stains like
Congo red violet and high of Flavin tea
fluorescent technique point number 32
Congo red staining is the gold standard
for the diagnosis of amyloidosis biopsy
is usually taken from the gingiva or the
rectal tissue or any other suspected
involved issue
oh here amyloid shows apple-green
birefringence under polarized light
thank you